As going down to micro scales, the basic hypothesis in the macro scale fluid mechanics may not be applicable in such scales. The objectives of this course are: to identify dominant forces and their effects in micro scale fluid systems that are different from those in the macro scales; to understand the fundamentals of micro fluidic phenomena; to discuss various microfluidic applications in research and commercial levels; and to explore new possible microfluidic applications in the emerging fields. Topics include overview of microfluidics, scaling laws, violation limit of the Navier-Stokes equations, surface force, surface tension, electrowetting, electrokinetics, dielectrophoresis, and soft lithography. Prerequisite: MAE 2314 and MAE 3310 or equivalents.