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CHEMĀ 5334. GENES, GENOME, AND REACTION MECHANISM. 3 Hours.

Concepts of Gene and genome in prokaryotes and eukaryotes; Gene regulation and epigenetics; Promoter architecture, transcription, mRNA processing and translation Histone modification, chromatin organization and non-coding RNA; Vitamins, hormones and Cell signaling; Transition states/Steady state; Pre-steady state kinetics; Mechanisms (ping-poing, bi-bi). Discuss current literature. Prerequisite: passing of ACS-test in Biochemistry.